LAP-BAND^® System Results

Thousands of patients. Millions of pounds. Real, lasting weight loss results.

There are two main ways people try to lose weight — the fast way, and the healthy way. Of course, the fast way may seem a dream come true. But like your dreams at night, this kind of weight loss doesn’t last. Using the LAP-BAND^® System, thousands of people have safely and effectively achieved healthy, lasting weight loss. In fact, a clinical study (N=100) showed that LAP-BAND^® System patients averaged up to a 59% reduction in excess weight after eight years.^1† And, another study showed that after the first year, 94.1% of patients were satisfied with the LAP-BAND AP^® System (N=272).^2‡

What you can expect

The LAP-BAND^® System is powerful tool that can give you control and help you lose weight. However, it’s also important to set realistic achievable weight loss goals from the start. Although weight loss of up to three pounds a week is possible, LAP-BAND^® System patients generally average a healthy one-to-two pound reduction a week.³ Best of all, once patients meet their target weight, they often maintain it for years.

Slow and steady = healthy and lasting

In addition to being temporary, losing weight too quickly can create health risks and lead to other problems. With the LAP-BAND^® System, the main goal is gradual, steady, and lasting weight loss that may prevent, improve, or resolve health problems associated with severe obesity.^1,4,5

With LAP-BAND^® you will lose less lean muscle mass and bone mass than with gastric bypass.^6,7 This means that most of your weight loss after LAP-BAND^® surgery is due to excess fat loss and that you will maintain more of the lean muscle mass you need to keep your metabolism working effectively which will help you to reach and maintain your weight loss goal. There is less risk of excessive bone loss leading to bone disease such as osteoporosis than with gastric bypass.^6,7 Gastric bypass and sleeve gastrectomy patients often need to take supplements to offset higher levels of lean muscle mass and bone density loss.

Proven Results

In an ongoing study (N=500), the LAP-BAND^® System was shown to provide significant reductions in weight. After 12 months (N=276)⁸:

• The mean Excess Weight Loss (EWL) was 47.5%^†
• The mean reduction in Body Mass Index (BMI) was 8.9 points^†
• At 12 months there was no sign of weight regain or hitting a plateau (weight loss leveling off)

In separate studies each evaluating one obesity-related health condition, weight loss with the LAP-BAND^® System was shown to help improve and resolve conditions such as asthma (93%; N=32), Type 2 diabetes (90%; N=50), sleep apnea (93%; N=123), gastroesophageal reflux (90%; N=48), and hypertension (79%; N=34).^9-12§

In an international study (N=272) reviewing long-term results of multiple studies over a 5-year period, LAP-BAND^® System patients lost 55% of their excess weight.^1,12†

In a separate study (N=276), comparable weight loss results (43% EWL) with the Realize^™ Band were shown after three years.¹⁴

For those with a Body Mass Index (BMI) between 30 and 40, a new study (N=149) shows that the LAP-BAND^® System provides significant results.¹⁵

In the first 12 months (N=143):

• The mean Excess Weight Loss (EWL) was 64.5%
• The mean reduction in Body Mass Index (BMI) was 6.5 points
• The mean reduction in waist circumference (in inches) for men was 6.1 inches; women 5.9 inches
• Weight loss was maintained at year 2

Weight loss with the LAP-BAND^® System is comparable to standard gastric bypass at 3 years and beyond¹

1. O’Brien PE, et al. Systematic review of medium-term weight loss after bariatric operations. Obes Surg. 2006;16(8):1032-1040.
2. Data on File. Allergan, Inc. Irvine, CA. October, 2009.
3. A Surgical Aid in the Treatment of Morbid Obesity, LAP-BAND^® System Information for Patients (P/N 94829). Allergan, Inc. Irvine, CA. April, 2008.
4. Weight-control Information Network (WIN), an information service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Do you know the health risks of being overweight? November 2004. Available at: http://win.niddk.nih.gov/publications/health_risks.htm. Accessed June 6, 2007.
5. Frigg A, Peterli R, Peters T, Ackerman C, Tondelli P. Reduction in co-morbidities 4 years after laparoscopic adjustable gastric banding. Obes Surg. 2004;14:216-223.
6. Chaston TB, Dixon JB, O’Brien PE. Changes in fat-free mass during significant weight loss: a systematic review. Int J Obes (Lond). May 2007;31(5):743-750.
7. Dixon JB, O’Brien PE. Nutritional Outcomes of Bariatric Surgery. In: Buchwald H, Cowan GSM, Pories WJ, eds. Surgical Management of Obesity. Philadelphia, PA: Saunders Elsevier; 2007:357-364.
8. Data on File. Allergan, Inc. Irvine, CA. November, 2010.
9. Dixon JB, Chapman L, O’Brien P. Marked improvement in asthma after Lap-Band® surgery for morbid obesity. Obes Surg. 1999;9:385-389.
10. Dixon JB, O’Brien PE. Health outcomes of severely obese type 2 diabetic subjects 1 year after laparoscopic adjustable gastric banding. Diabetes Care. 2002;25:358-363.
11. Dixon JB, Schachter LM, O’Brien PE. Sleep disturbance and obesity. Arch Intern Med. 2001;161:102-106.
12. Dixon JB, O’Brien PE, Gastroesophageal reflux in obesity: the effect of Lap-Band placement. Obes Surg. 1999;9:527-531.
13. Directions For Use (DFU). LAP-BAND AP^® Adjustable Gastric Banding System with OMNIFORM^® Design. Allergan, Inc. Irvine, CA. 02/11. The LAP-BAND^® System was approved in the United States on the basis of a nonrandomized, single-arm study (N=299). Significant improvement in percent of excess weight loss vs. baseline was achieved at 12 months (34.5%), 24 months (37.8%), and 36 months (36.2%).
14. REALIZE™ Adjustable Gastric Band Instructions for Use ©Obtech Medical Sàrl 2008 74110 IFU-74110.
15. Data on File. Allergan, Inc. Irvine, CA. December, 2010.
16. Weight-control Information Network (WIN), an information service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Statistics related to overweight and obesity. June 2007. Available at: http://win.niddk.nih.gov/statistics/index.htm. Accessed August 13, 2007.
17. Sturm R. The effects of obesity, smoking and problem drinking on chronic medical problems and health care costs. Health Aff. 2002; 21(2):245-253.
18. O’Brien PE, et al. LAP-BAND^®: Outcomes and Results. J Laparoendosc Adv Surg Tech A. 2003; 13(4):265-270.